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Plasma mitochondrial DNA is elevated in maternal serum at first trimester and may serve as a biomarker for prediction of gestational diabetes mellitus.

J Diabetes · 2023 · PMC10755614 · PMID 37658630

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Though ΔCt ND4 was higher in the GDM‐positive group, the levels did not reach statistical significance. ΔCt D‐loop was similar in GDM‐positive cases and controls who did not develop GDM during pregnancy.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.