In addition, sTie1 levels showed a trend towards increased levels in patients with SLE.
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Type I Interferons induce endothelial destabilization in Systemic Lupus Erythematosus in a Tie2-dependent manner.
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The sentences
We also analysed the expression of several adhesion proteins during angiogenic process ( 33 ), where we found a significant (p<0.0001 and p=0.0007) increase in ICAM and VCAM after 24 h of stimulation, as well as an increasing trend in CD141 and Claudin5 ( Figure 5E ).