Mendelian randomization indicates causal effects of estradiol levels on kidney function in males.

Front Endocrinol (Lausanne) · 2023 · PMC10758447 · PMID 38169598

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highly significantno p-value reported

However, our GWAS revealed a highly significant association on chromosome 14 (rs7151019), which was used as instrument in the one-sample MR.

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did not reach statistical significanceno p-value reported

We revealed significant results with eGFR in postmenopausal women and with UACR in premenopausal women, which did not reach statistical significance in the sensitivity MR analyses.

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