Short-term effectiveness of single-dose intranasal spray COVID-19 vaccine against symptomatic SARS-CoV-2 Omicron infection in healthcare workers: a prospective cohort study.

It is noteworthy that dNS1-RBD vaccination substantially decreased the incidence of some symptoms with grade 3 or above, which include fever, cough, anorexia, nausea, vomiting, sore throat, headache, and chest tightness/shortness of breath, but most differences did not reach statistical significance due to the limited number of cases within each group ( Table S2 ).

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