Characterization of human transcription factor function and patterns of gene regulation in HepG2 cells.

In some cases, predicted activators did have a lower activity level than did the matched controls, but we note that these cases were almost universally nominally significant ( P ≤ 0.05) (see asterisk in Supplemental Fig. 20 ; Supplemental Table 15 ), with ZNF501, ZFX, ZFY, and ASH2L showing a greater degree of discordance with predictions.

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