The steroid hormone ADIOL promotes learning by reducing neural kynurenic acid levels.

However, we note that while, compared with nontransgenic controls, ADIOL treatment consistently enhanced learning in nhr-91 mutants in which nhr-91 was specifically reconstituted in the RIM neurons, the enhancement of learning induced by ADIOL in the transgenic animals did not reach statistical significance compared with the DMSO treatment of these transgenics.

also in 111,027 other papers