Control: t = 5.53, P = 0.0002). OPRM1 mRNA expression changes (shown by post hoc t-tests) due to CIE exposure or CIE exposure + WD showed a trend like the OPRM1 mRNA methylation changes ( Figure 2b ).
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Chronic intermittent ethanol exposure-induced m6A modifications around mRNA stop codons of opioid receptor genes.
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