A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts.

Mol Med · 2024 · PMC10765874 · PMID 38172668

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slightly significantno p-value reported

We only found a slightly significant increase in RHEB levels of LND fibroblasts cultivated with physiological levels of FA but it did not translate into increased levels of the mTORC1 effector protein pS6 (Fig. 5 ).

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