Psychological interventions to improve pain, fatigue, anxiety, depression, and quality of life in children and adults with hypermobility spectrum disorders and Ehlers-Danlos syndrome: a systematic review.

The third study [ 22 ] simply asked patients to rate their fatigue on a scale from “no disability” to “worst imaginable”, with a small difference observed at 1-month follow-up that did not reach statistical significance ( F (2, 101) = 2.141, p > 0.05; partial η 2 = 0.041).

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