Redirecting antibody responses from egg-adapted epitopes following repeat vaccination with recombinant or cell culture-based versus egg-based influenza vaccines.

In contrast, among recipients of non-egg-based vaccines in just one study year (IIV4-ccIIV4 or IIV4-RIV4) or in both study years (ccIIV4-ccIIV4, ccIIV4-RIV4, RIV4-ccIIV4, RIV4-RIV4), the proportions of participants with egg/cell ratio ≥4 to generally decreased post-vaccination though did not reach statistical significance in some repeat vaccination groups (Fig. 7 ).

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