moderately significantp < .05
The mean expression levels between the groups showed highly significant differences for five proteins (sTNFRI, sTNFRII, IGFBP2, IGFBP6, IGFBP1; p < 1 × 10 −4 ) and moderately significant differences for three proteins (IGFBP3, CRP, SAA; p < .05) (Supporting Information: Table 1 and Supporting Information: Figure 1 ).