Interestingly, coagulation-related genes showed highly significant enrichment in KRAS, CDKN2B, KEAP1, MET and STK11 mutant tumors when compared to their WT counterparts.
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Oncogenes and cancer associated thrombosis: what can we learn from single cell genomics about risks and mechanisms?
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Multiple effectors showed a trend of upregulated expression in tumor alveolar cell subsets in comparison to normal alveolar cells ( Figure 1D ).