The Impact of BRCA1 Expression on Survival Status in Ovarian Serous Carcinoma of Egyptian Patients.

Asian Pac J Cancer Prev · 2023 · PMC10770685 · PMID 37898870

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0700

boldest claim

The sentences

highly significantp < 0.0001actually significant

There is a highly significant increase in age, in positive BRCA1 group; compared to negative BRCA1 group (p < 0.0001) while a non-significant difference as regards all the remaining basic clinical data (history of breast cancer, laterality, presenting symptoms and CA125 level) (p > 0.05) was found.

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showed a trendP=0.07so close (0.05 < p ≤ 0.1)

In contrast, Kalachand et al., 2020 revealed that patients with BRCA1 /2-mutated tumors showed a trend toward improved DFS as compared to those with BRCA1 /2-intact tumors (median survival: 17 vs. 6 months [HR, 0.48;95% CI, 0.22–1.06; P=0.07] and 20 vs. 11 months [HR, 0.53;95% CI, 0.26–1.09; P=0.08], respectively).

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