Regarding liquid intake, cisplatin caused a slight increase and vincristine a slight decrease compared with their respective controls, but these differences did not reach statistical significance ( Figures 3D, F ). 3.2 Colonic contractility in organ bath 3.2.1 Preparations used in the study Four preparations of each muscle (LM and CM) were initially obtained from each animal, but only those that reached the preset threshold of PA contractile response to KCl 50 mM and did not rupture during the experiment were used in the study.
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Contractility of isolated colonic smooth muscle strips from rats treated with cancer chemotherapy: differential effects of cisplatin and vincristine.
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