Characterization of immunomodulating agents from Staphylococcus aureus for priming immunotherapy in triple-negative breast cancers.

Consistent with their known activity, our flow cytometric analysis revealed that six days following their injections into 4T1 tumors, both PSM⍺3 and Protein A showed a trend of increasing CD11b + Ly6G + Ly6C low cells, which represent PMNs and granulocytic myeloid-derived suppressor cells (gMDSCs) (Supplementary Fig. 2 A).

also in 53,322 other papers

Moreover, injections of > 1 kD molecules affected the composition of T cells where CD8 + populations displayed an increasing trend and CD4 + populations were significantly reduced (Fig. 1 B).

also in 63,971 other papers