A trend toward worse OS for wedge resection versus lobectomy was seen in all subgroups, likely reflecting the nonrandomized choice of surgical approach in this retrospective cohort, but the differences did not reach statistical significance ( Table 3 ).
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Vascular invasion predicts the subgroup of lung adenocarcinomas ≤2.0 cm at risk of poor outcome treated by wedge resection compared to lobectomy.
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