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Overcoming resolution attenuation during tilted cryo-EM data collection.

Nat Commun · 2024 · PMC10776679 · PMID 38195598

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As expected, the resulting reconstructions showed a clear trend of decreasing resolution as the tilt angle is increased (Fig. 1a ); at 0° stage tilt, the resolution is 2.3 Å, but the resolution drops to 2.8 Å at 30° stage tilt, and 4.0 Å at 60° stage tilt.

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