Effects of Semaglutide on Symptoms, Function, and Quality of Life in Patients With Heart Failure With Preserved Ejection Fraction and Obesity: A Prespecified Analysis of the STEP-HFpEF Trial.

Circulation · 2024 · PMC10782938 · PMID 37952180

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did not reach statistical significanceno p-value reported

Fewer semaglutide-treated versus placebo-treated patients experienced ≥5-point deterioration across KCCQ domains (although these results did not reach statistical significance for OSS and QoLS).

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