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Administration of an AAV vector coding for a P2X7-blocking nanobody-based biologic ameliorates colitis in mice.

J Nanobiotechnology · 2024 · PMC10785547 · PMID 38212782

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Mice injected with AAV-14D5-dimHLE exhibited a trend toward a worsening of disease as compared to untreated mice that did not reach statistical significance, possibly reflecting an already very high level of inflammation.

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