Although intratumoal TILs showed marginal increases in CRC patients with higher peritumoral TILs, these did not reach statistical significance (CD3+TILs TC vs CD3+TILs IM , P = 0.535; CD3+TILs TC vs CD3+TILs TS , P = 0.240; CD8+TILs TC vs CD8+TILs IM , P = 0.093; CD8+TILs TC vs CD8+TILs TS , P = 0.058).
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Clinical impact of heterogeneously distributed tumor-infiltrating lymphocytes on the prognosis of colorectal cancer.
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