Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes.

S3), as well as a highly significant negative genetic correlation between c-intensity and age at menarche (rg = − 0.52, P = 6.72 × 10 −23 ), indicating that genetic determinants of later pubertal onset also favor a slower tempo of growth.

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We performed validation analyses in the UK Biobank, selecting 37 traits that demonstrated either significant LDSC-based genetic correlations or nominally significant associations in the PMBB.

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