Similarly, when the transient silencing of Mgmt was performed 48 h prior to BG treatment, significantly enhanced IL-6 productions were observed whereas slight increase in TNFα level was observed but the levels did not reach statistical significance ( Figures S1 D and S1F).
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O<sup>6</sup>-methylguanine DNA methyltransferase regulates β-glucan-induced trained immunity of macrophages via farnesoid X receptor and AMPK.
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