Overexpression of TFEB also showed a trend of increased expression of several autophagy-related genes and lysosomal genes including Sqstm1 , Atg5 , Atg8 , Lamp1 , Vatp6v1d , Vatp6v0e1 and Vatp6v1h with or without APAP treatment ( Fig. 4 C).
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High-throughput screening of novel TFEB agonists in protecting against acetaminophen-induced liver injury in mice.
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