Human APOE4 Protects High-Fat and High-Sucrose Diet Fed Targeted Replacement Mice against Fatty Liver Disease Compared to APOE3.

Aging Dis · 2024 · PMC10796091 · PMID 37450924

Europe PMC DOI

hedged sentences

0.0740

closest p · 1.5× alpha

0.0920

boldest claim

The sentences

borderline significancep=0.074so close (0.05 < p ≤ 0.1)

Likewise, the difference in mRNA levels of Icam1 , a gene encoding a surface marker for leukocyte adhesion, and P2rx7 , encoding the damage associate molecular pattern (DAMP) receptor P2X purinoceptor 7 for extracellular ATP, reached only borderline significance (p=0.074 and p=0.089, respectively).

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did not reach statistical significancep=0.092so close (0.05 < p ≤ 0.1)

The induction of Cd2 mRNA expression, a marker of T-cells and natural killer cells, did not reach statistical significance due to the very high interindividual variation (p=0.092).

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