Engineered cocultures of iPSC-derived atrial cardiomyocytes and atrial fibroblasts for modeling atrial fibrillation.

Sci Adv · 2024 · PMC10798559 · PMID 38241367

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did not reach statistical significanceno p-value reported

Dofetilide, a class III AAD that targets I kr and prolongs the effective refractory period ( 35 ), caused an increase in APD 90 in both RM and PC, but the increase in RM did not reach statistical significance for one of the two iPSC-aCM donors.

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