Dissecting tumor microenvironment heterogeneity in syngeneic mouse models: insights on cancer-associated fibroblast phenotypes shaped by infiltrating T cells.

Front Immunol · 2023 · PMC10800379 · PMID 38259467

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Among these, Cxcl12 was significantly upregulated in the immunocompetent tumors, and there was a clear trend towards an upregulation of Il6 and Cd274 (PD-L1) ( Figure 6F ).

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