Barely Significant
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Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice.

Front Cardiovasc Med · 2023 · PMC10800928 · PMID 38259303

Europe PMCDOI
1
hedged sentence
0.0540
closest p · 1.1× alpha
0.0540
boldest claim

The sentences

showed a trendp = 0.054so close (0.05 < p ≤ 0.1)
Picrosirius Red (PSR) staining of histological cross-sections showed a trend towards interstitial fibrosis ( p = 0.054) ( Supplementary Figure S2J ), which was paralleled by an increased expression of the extracellular matrix proteins Collagen alpha-1(I) chain ( Col1a1 ) and Fibronectin ( Fn ) whereas Collagen alpha-1(III) chain ( Col3a1 ) and connective tissue growth factor ( Ctgf ) remained unchanged in cKO compared to WT mice ( Supplementary Figure S2K ).

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