Influence of Season, Storage Temperature and Time of Sample Collection in Pancreatitis-Associated Protein-Based Algorithms for Newborn Screening for Cystic Fibrosis.

Immediately after birth, PAP values were lowest and then showed an increasing trend ( Figure 3 ).

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Our data, obtained over 7 years (2009–2015), show that the averaged PAP values also tended to be slightly lower in summer than in winter in 6 out of 7 years ( Figure 1 , Table A2 in Appendix A ), but the differences did not reach statistical significance.

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