Leptin signaling in the dorsomedial hypothalamus couples breathing and metabolism in obesity.

Cell Rep · 2023 · PMC10804286 · PMID 38039129

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may be significantno p-value reported

90 However, our study suggests that leptin-mediated serotonergic pathways may be significant in the settings of obesity hypoventilation combined with upper airway obstruction (90% of patients with OHS and 10%–40% of obese OSA patients).

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did not reach statistical significanceno p-value reported

J60 significantly increased V E during NREM sleep ( Figure 1J ), although changes in tidal volume (V T ) and respiratory rate (RR) did not reach statistical significance.

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