Antibiotic Protocols for Endophthalmitis Prophylaxis Following Open-Globe Repair: A Survey of U.S. Residency Programs.

The rate of endophthalmitis in this study was found to be 2.2%, excluding those patients that had endophthalmitis at presentation. 17 The role of intravitreal antibiotics for endophthalmitis prophylaxis in OGI repair has not been well described and is often reserved for OGI with high-risk characteristics. 18 Abouammoh et al analyzed and compared rates of posttraumatic endophthalmitis before and after their protocol was changed to include intravitreal antibiotics and found improvements in endophthalmitis rates (3.7 vs 1.7%) that did not reach statistical significance ( p = 0.077). 19 There is evidence to support the use of IV, oral, and intravitreal antibiotics as a primary or adjunct tool in the prevention of endophthalmitis and severe vision loss for patients with traumatic OGI.

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