Temporal analysis and spatial distribution of acquired syphilis in the state of Mato Grosso, Brazil, 2010-2021: an ecological study.

DISCUSSION This study showed an increasing trend in acquired syphilis in the state of Mato Grosso, in the period between 2010 and 2021, particularly in the last two three-year periods of the series (2016-2018 and 2019-2021), despite Ministry of Health initiatives to combat the disease with effect from 2016. 1 ),( 5 ),( 19 Our analysis of detection rates during the study period showed that the Southern macro-region had the lowest rates, while the Central-North macro-region had the highest rates throughout the time series.

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The joinpoint analysis showed that, in the West, North and East macro-regions, there was a strong trend of rising rates until the middle of the study period (2018-2019), when the curves inflected, and began to show a falling trend ( Table 1 ).

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