Pharmacological and non-pharmacological interventions for irritability in autism spectrum disorder: a systematic review and meta-analysis with the GRADE assessment.

Mol Autism · 2024 · PMC10807060 · PMID 38263251

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did not reach statistical significanceno p-value reported

Meta-analysis on risperidone + dietary supplementation ( N -acetylcysteine, sulforaphane, L-carnosine, and Ginkgo biloba) compared to risperidone did not reach statistical significance ( k = 5, Hedges’ g − 0.490, 95% CI − 1.045 to 0.066, certainty of evidence: very low).

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