Recombinant BCG vaccine expressing multistage antigens of <i>Mycobacterium tuberculosis</i> provides long-term immunity against tuberculosis in BALB/c mice.

Hum Vaccin Immunother · 2024 · PMC10807470 · PMID 38258510

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In regard to the innate immune-related cytokines, rBCG-ECD003 showed a trend to induce higher IL-17 ( p < .05) and GM-CSF ( p < .01) levels compared to BCG groups at the 4 th week, but not shown at the 12 th week.

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