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MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression.

JCI Insight · 2023 · PMC10807718 · PMID 37971875

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Our findings also generally agree with a more recent study using whole-genome sequencing data from TCGA samples that showed a trend for increased mtDNAcn in prostate cancer versus benign matched tissues ( 45 ).

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