Blockade of Nrp1 receptor function in si Htatip2 -iBMMs was also associated with reduced intracellular pERK signaling in response to VEGFA stimulation ( Figure 5, E and F ) compared with Nrp1-functioning si Htatip2 -iBMMs (fold-change, 1.6 versus 2.1), but this did not reach statistical significance.
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HTATIP2 regulates arteriogenic activity in monocytes from patients with limb ischemia.
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