Effect of istradefylline on postural abnormalities in patients with Parkinson's disease: An association study of baseline postural angle measurements with changes in Unified Dystonia Rating Scale total score.

Although the change in the UDRS total score in patients with below-median values for TFFA and TLFA did not reach statistical significance, a remarkable decrease was noted in the UDRS total score at week 24 compared with that at week 0, suggesting that PAs may be improved with istradefylline treatment even in patients with mild symptoms.

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