Crossroads between Skin and Endocrine Glands: The Interplay of Lichen Planus with Thyroid Anomalies.

Five case-control studies [ 47 , 48 , 50 , 71 , 72 ] addressed the issue of levothyroxine replacement for a prior endocrine condition in patients that were diagnosed with OLP (no study on LP was identified according to our methods); three of them [ 47 , 71 , 72 ] confirmed a higher rate of this treatment in OLP (at 8.9%, 9.7%, and 10.6%) versus controls, while the other two did not reach statistical significance [ 48 , 50 ].

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