Barely Significant
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Shift in Tissue-Specific Immune Niches and CD137 Expression in Tuberculoma of Pembrolizumab-Treated Nasopharyngeal Carcinoma Patients.

Cancers (Basel) · 2024 · PMC10813936 · PMID 38254759

2
hedged sentences
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

marginally significantp = 0.06so close (0.05 < p ≤ 0.1)
Additionally, the frequencies of group 2 cells (CD137+ IFNγ+ CD8+ T cells) were higher in cluster 3 (G) tissues compared to cluster 2 (M) tissues (marginally significant, p = 0.06).

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Although these findings did not reach statistical significance, they suggest that the presence of Ki67+Eomes+ and Ki67+PD1+ T cell subsets in the TME of NPC may suggest susceptibility to irAE.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.