Long Interspersed Nuclear Element-1 Analytes in Extracellular Vesicles as Tools for Molecular Diagnostics of Non-Small Cell Lung Cancer.

Int J Mol Sci · 2024 · PMC10816871 · PMID 38256242

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0630

boldest claim

The sentences

borderline significantp = 0.056so close (0.05 < p ≤ 0.1)

Mean LINE-1 mRNA levels were generally higher in females, with EV LINE-1 mRNA content in females at 0.26 log2 FC relative to RTC, which was borderline significant ( p = 0.056) compared to males, with a mean of 0.053 log2 FC relative to RTC.

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near-significantp = 0.063so close (0.05 < p ≤ 0.1)

Remarkably, a significant relationship between bulk plasma ELISA and EV LINE-1 mRNA levels was found ( R 2 = 0.41, p = 0.024), along with a near-significant relationship with EV ORF1p levels ( R 2 = 0.30, p = 0.063).

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