MVA-based vaccine candidates encoding the native or prefusion-stabilized SARS-CoV-2 spike reveal differential immunogenicity in humans.

NPJ Vaccines · 2024 · PMC10817990 · PMID 38278816

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did not reach statistical significanceno p-value reported

In contrast, a third mRNA vaccination boosted the B cell response in the mRNA (S1: mfc [SFC] = 8.8; S2: mfc [SFC] = 5.8) and ChAd/mRNA (S1: mfc [SFC] = 5.0; S2: mfc [SFC] = 7.3) control cohorts, but this did not reach statistical significance.

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