Gut microbiota does not play a mediating role in the causal association between inflammatory bowel disease and several its associated extraintestinal manifestations: a Mendelian randomization study.

Front Immunol · 2023 · PMC10822939 · PMID 38288127

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nominally significantno p-value reported

A total of 67 causal associations were identified as nominally significant in intestinal flora and eight extraintestinal manifestations, i.e., 5 in sarcoidosis, 12 in iridocyclitis, 13 in interstitial lung disease, 10 in atopic dermatitis, 9 in ankylosing spondylitis, 5 in psoriatic arthritis, 5 in PSC, and 8 in PBC.

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