Murine cartilage microbial DNA deposition occurs rapidly following the introduction of a gut microbiome and changes with obesity, aging, and knee osteoarthritis.

Phylum Verrucomicrobia was increased in HFD ( P = 0.004), aging ( P = 0.03), HFD in old animals ( P = 0.02), and OA ( P = 0.04, Verrucomicrobia did not reach statistical significance in cecal 16S-OA data).

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