Integrative polygenic analysis of the protective effects of fatty acid metabolism on disease as modified by obesity.

Front Nutr · 2023 · PMC10832455 · PMID 38303904

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nominally significantno p-value reported

A nominally significant p -value threshold of 0.05 was applied using the inverse variance weighted (IVW) MR method to determine significant associations ( 16 ).

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highly significantno p-value reported

Conversely, endocrine/metabolic disease, particularly type 2 diabetes, shows the opposite trend, showing a highly significant interaction between WHR or BMI and DHA that is less obvious for the genetic component of the metabolite.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.