Protective role of curcumin in disease progression from non-alcoholic fatty liver disease to hepatocellular carcinoma: a meta-analysis.

The meta-analysis suggested a trend of increased HDL-C levels in the curcumin group compared to that in the model group, although it did not reach statistical significance [SMD = 1.21, 95% CI (−0.04, 2.45), p = 0.057] ( Supplementary Figure S1B ). 3.4.3 The effect on serum insulin, glucose, and HOMA-IR As for the index of serum insulin ( I 2 = 92.4%, p < 0.0001), glucose ( I 2 = 89.3%, p < 0.0001), and HOMA-IR ( I 2 = 83.2%, p = 0.003), curcumin could remarkably reduce the insulin level compared to the model group, but there was no significance [ SMD = −1.10, 95 % CI (−3.36, 1.16), p = 0.34] ( Supplementary Figure S2A ).

also in 111,027 other papers