Surgical and local control outcomes after sequential short-course radiation therapy and chemotherapy for rectal cancer.

In univariate analysis, duration of chemotherapy (< 12 weeks or ≥ 12 weeks), interval from completion of radiation to surgery modeled as a continuous variable, and type of surgery were of borderline significance.

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Two-year local control was indeed numerically inferior in the high-risk group- 90.4 % versus 97.6 % in the low-risk group, although this difference did not reach statistical significance.

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