Barely Significant
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BNT162b2 versus mRNA-1273 Third Dose COVID-19 Vaccine in Patients with CKD and Maintenance Dialysis Patients.

Clin J Am Soc Nephrol · 2024 · PMC10843183 · PMID 37847518

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hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)
Secondary Outcome Measures SARS-CoV-2 Antispike Binding IgG Levels Third dose mRNA-1273 induced higher mean anti-spike levels during follow-up: 1.03 relative ratio; 95% CI, 0.86 to 1.18 (1553 BAU/ml; 95% CI, 1240 to 1849) in comparison with a third dose BNT162b2: 0.97 relative ratio; 95% CI, 0.80 to 1.12 (1444 BAU/ml; 95% CI, 1132 to 1740), although this difference of 0.06 relative ratio; 95% CI, −0.02 to 0.12 (110 BAU/ml; 95% CI, −5 to 219) did not reach statistical significance ( P = 0.06) likely due to signal saturation above a relative ratio of 1.2.

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