Barely Significant
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Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model.

Neurobiol Dis · 2024 · PMC10843801 · PMID 37992782

Europe PMCDOI
3
hedged sentences
0.0510
closest p · 1.0× alpha
0.0620
boldest claim

The sentences

approached significancep = 0.051so close (0.05 < p ≤ 0.1)
On P3, trisomic females continued to show elevated DYRK1A that was significant in the forebrain ( p = 0.028; d = 1.04) and approached significance in the cerebellum ( p = 0.051; d = 0.88), whereas the males continued to show no significant differences in either region ( Fig. 1C ).

also in 1,232 other papers

a trend toward significancep = 0.062so close (0.05 < p ≤ 0.1)
Dyrk1a copy number reduction in the male euploid mice (Eu, Dyrk1a +/− ) did not significantly affect DYRK1A expression in the cerebral cortex or cerebellum, but there was a trend toward significance in the hippocampus ( p = 0.062; d = 0.97).

also in 619 other papers

failed to reach significanceno p-value reported
All other outcomes failed to reach significance, and for those outcomes the effect sizes ranged from 0.22 to 0.86. 3.2.

also in 573 other papers

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