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Recurrent Colorectal Liver Metastases: Upfront Local Treatment versus Neoadjuvant Systemic Therapy Followed by Local Treatment (COLLISION RELAPSE): Study Protocol of a Phase III Prospective Randomized Controlled Trial.

Cardiovasc Intervent Radiol · 2024 · PMC10844349 · PMID 37943351

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showed a trendno p-value reported
A recent pooled meta-analysis showed a trend towards improved survival with the addition of neoadjuvant systemic therapy to repeat local treatment [ 24 ].

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