Although statistically non-significant, the presence of either drug resulted in a clear trend in increased population of bacteria being entrapped in the perforated BCVs (Supplementary Fig. 1 , “Entrapped”) and a decrease in the occurrence of Shigella moving free of any membrane remnants (Supplementary Fig. 1C , “Free”).
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Microtubules provide force to promote membrane uncoating in vacuolar escape for a cyto-invasive bacterial pathogen.
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