Barely Significant
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Nuclear damage in <i>LMNA</i> mutant iPSC-derived cardiomyocytes is associated with impaired lamin localization to the nuclear envelope.

Mol Biol Cell · 2023 · PMC10846625 · PMID 37585285

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hedged sentence
0.3000
closest p · 6.0× alpha
0.3000
boldest claim

The sentences

did not reach statistical significancep > 0.3not close (p > 0.1)
On the other hand, the L35P and G449V mutant iPSC-CMs, which had milder defects in nuclear shape and size, showed no increase in nuclear-envelope rupture or only a trend towards increased nuclear-envelope rupture (G449V) that did not reach statistical significance ( p > 0.3 vs. healthy controls).

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